Home » Anadrol vs Dbol- one of the best ways to compare

Anadrol vs Dbol- one of the best ways to compare

Anadrol vs Dbol- one of the best ways to compare

Medication can be described as a drug or a form of medicine that is used either to prevent and
disease or to recover from the disease. Medications work both, prophylaxis and treatment too. The drugs or medication which are used to prevent any diseases are known as prophylactic
medications and the medicines which are used to treat and recover from the diseases falls under the
treatment drugs.


Medication is a substance that is used or taken into our body that potentially cures diseases and medical conditions. For example, antibiotics are taken to prevent and cure any bacterial,
fungal or viral infections. Anti-inflammatory drugs and antipyretic drugs are basically used either to
cure any kind of inflammation in our body or and for fever. The anti-inflammatory drugs are a vast
subject of pharmacology- basically concerned with the study of formulation, mechanism, uses
advantages and disadvantages of any drug along with its side effects. The anti-inflammatory drugs
are mainly classified as steroidal and non-steroidal drugs.

Steroidal anti-inflammatory drugs are known as steroidal pain killers which are professionally
prescribed by the specialist doctor with proper dosage. For example- prednisolone, betamethasone,
dexamethasone, hydrocortisone, methylprednisolone and deflazacort. These medicines are
commonly corticosteroids that are used to treat and cure a different range of diseases like severe
muscular or acute pain and are also used in increasing muscle mass. These medications also treat
systemic conditions like systemic vasculitis- inflammation of the blood vessels, myositisinflammation of muscles. These are potentially active drugs to cure inflammatory conditions
such as rheumatoid arthritis and lupus erythematosus.

Anadrol is a steroid medication with a core compound of Oxymetholone sold under the names of
Anadrol and anapolon in the market. It is an androgen and anabolic steroid medication, it’s a
powerful steroid that is primarily used to treat anaemia. It is also used to treat different systemic conditions like osteoporosis, human immunodeficiency virus- HIV, AIDS- autoimmunosuppressive dysfunction syndrome, muscle wasting and many more. It is also used to promote the overall growth of the body by increasing the core muscle mass.
Formula- C21H32O3
Drug classified as- androgen and anabolic steroid
Metabolism- by the liver
Bioavailability- it is well absorbed
Molar mass- 332.484 gmol-1
Medicinal uses

The primary clinical uses of oxymetholone include treatment of anaemia and osteoporosis, as well as
stimulating muscle growth in malnourished or underdeveloped patients. In the United States, as per
the research, it is believed to be the only remaining FDA-approved indication is the treatment of
anaemia. Oxymetholone and the combination of nonsteroidal drugs such as epoetin alfa were
developed and approved to be more effective as a treatment for anaemia and osteoporosis without
the side effects of oxymetholone. The drug remained available for a longer time and despite this, it
was eventually found a new use in treating HIV/AIDS wasting syndrome.

The drug is commonly
presented as a 50 mg tablet, oxymetholone has been said to be one of the “strongest” and “most
powerful” and also most potential AAS available for medical use. Oxymetholone is highly effective in
promoting extensive gains and boost body mass, mostly by greatly improving protein synthesis.
For such a potential reason, it is most often used by bodybuilders and athletes.
Non-medicinal uses

Oxymetholone due to its magical structure is also used for physique-and performance-enhancing
purposes by many competitive athletes, bodybuilders, and powerlifters.

Side effects

The most common side effects of oxymetholone include a variety of
depression, lethargy, headache, swelling, rapid weight gain, priapism, changes in skin colour,
urination problems, nausea, vomiting, stomach pain when taken on an empty stomach, loss of
appetite. The other common side effects include jaundice, breast swelling in men, feeling restless or
excited, insomnia, and diarrhoea. In women side effects majorly include acne, changes in menstrual
periods, voice deepening, hair growth on the chin or chest, pattern hair loss, enlarged clitoris, and
changes in libido. Because of its 17α-alkylated structure, oxymetholone is hepatotoxic. Long term
use of the drug and routine use can cause a variety of serious ailments, including hepatitis, liver
cancer, and cirrhosis; therefore periodic liver function tests are recommended for those taking


Like other AAS, oxymetholone is an agonist of the androgen receptor (AR). It is not a substrate
for 5α-reductase and is further classified as a poor substrate for 3α-hydroxysteroid
dehydrogenase (3α-HSD), and therefore it shows a high ratio of anabolic to androgenic activity.
As an also DHT derivative, oxymetholone is not a substrate for aromatase and hence it cannot be
aromatized into estrogenic metabolites. However, uniquely among DHT derivatives, oxymetholone is
associated with relatively high iatrogenicity and is also known to have the potential to produce
estrogenic side effects such as gynecomastia which is very rare, and water retention also at times.
It has been suggested that this may be due to direct binding to the compound and activation of
the oestrogen receptor by oxymetholone drug. Oxymetholone does not possess any significant and
active progestogenic activity.


There is limited information available on the pharmacokinetics of oxymetholone. It appears to
be well-absorbed with oral administration which is of great ease. Oxymetholone has a very
low affinity for human serum sex hormone-binding globulin (SHBG), less than 5% of that of
testosterone and less than 1% of that of DHT which is an essential point for the drug with its
pharmacokinetics effect. The drug is metabolized in the liver by oxidation reaction at the C2
position, reduction at the C3 position, hydroxylation at the C17 position, and lastly conjugation. The
C2 hydroxy methylene group of oxymetholone can be cleaved to form mestanolone, which may
contribute to the effects of oxymetholone drug. The elimination half-life of oxymetholone is
unknown. Oxymetholone and its metabolites are passed out in the urine.
Dbol (methandienone)

Metandienone is also known as methandienone or by the other name methandrostenolone is
usually sold under the brand name of Dianabol. It is an androgen and anabolic steroid medication
that is still used by many people and prescribed because of its affordability and effectiveness for
bulking cycles.
Formula- C20H28O2
Molar mass- 300.441g/mol
Elimination and half-life- approximately 3 to 6 hours
Drug classification- androgen and anabolic steroid
Metabolism by the liver.
High bioavailability.

Metandienone medication was originally developed in 1955 by CIBA company and marketed
in Germany and the United States. As the CIBA product Dianabol, methandienone quickly became the
first widely used AAS among professional and amateur athletes and remains the most common
orally active AAS for non-medical use. It is currently a controlled substance in the United States
and the United Kingdom and remains popular among bodybuilders. Metandienone is readily available
without a prescription in certain countries such as Mexico and is also manufactured in
some Asian countries.

Medicinal uses

Metandienone was formerly approved and marketed as a form of androgen replacement therapy for
the treatment of hypogonadism in men. But it has been discontinued and withdrawn in most
countries, including in the United States. It was given at a dosage of 5 to 10 mg/day in men and
2.5 mg/day in women.

Non-medicinal uses

Metandienone drug has a unique structure that is used for physique- and performance-enhancing
purposes by competitive athletes, bodybuilders, and powerlifters. It is said to be the most widely
used AAS for such purposes both today and historically.
Side effectsAndrogenic drug has major side effects such as oily skin, acne, seborrhoea, increased facial as well as
body hair growth, scalp hair loss, and virilization may occur. The drug also includes Estrogenic side
effects such as gynecomastia and fluid retention. As with other 17α-alkylated steroids,
methandienone poses a high risk of hepatotoxicity and use over extended periods of time can result
in liver damage without appropriate precautions and care.


Metandienone binds actively to and activates the androgen receptor (AR) to exert its
effects. These include dramatic increases in some of the processes like protein
synthesis, glycogenolysis, and muscle strength over a short space of time. It can
be metabolized by 5α-reductase into methyl-1-testosterone which is a more potent AAS, the drug
has an extremely low affinity for this enzyme and methyl-1-testosterone is thus produced in only trace
amounts. As such, 5α-reductase inhibitors like finasteride and dutasteride do not reduce the
androgenic effects of methandienone. The ratio of anabolic to androgenic activity of methandienone is
improved relative to that of testosterone, the drug does still possess the moderate androgenic activity
and is capable of producing severe virilization in women and children. As such, it is only really commonly used in men.

Metandienone has high oral bioavailability. It has a very low affinity for human serum sex hormone-binding globulin (SHBG), about 10% of that of testosterone and 2% of that of DHT. The drug is metabolized in the liver by 6β-hydroxylation, 3α- and 3β-oxidation, 5β-reduction, 17-
epimerization, and conjugation among other reactions. Unlike methyltestosterone, owing to the presence of its C1(2) double bond, methandienone does not produce 5αreduced metabolites. The elimination half-life of methandienone is about 3 to 6 hours. It is eliminated in the urine.

also read: Dbol vs Anadrol: Which is the Best to Really Bulk Up Fast Between Anadrol vs Dianabol?

Anadrol vs Dbol
Anadrol as per the numerous studies generally giver better results when compared to Dbol. Anadrol is also tested as a more powerful steroid. Keeping in mind also, though Anadrol is proved to be having more side effects it is more effective and used.

About the author


Add Comment

Click here to post a comment

%d bloggers like this: